Pharmaceutical composition comprising GLP-1 agonist, insulin, and methionine

The invention relates to a pharmaceutical composition comprising a GLP-1 agonist, an insulin, and a methionine, and specifically to a liquid composition comprising a GLP-1 agonist or/and a pharmacologically tolerable salt thereof, an insulin or/and a pharmacologically tolerable salt thereof, and opt...

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Hauptverfasser: MUELLER WERNER, TERTSCH KATRIN, SIEFKE-HENZLER VERENA, HAGENDORF ANNIKA, SCHOETTLE ISABELL, HAUCK GERRIT
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a pharmaceutical composition comprising a GLP-1 agonist, an insulin, and a methionine, and specifically to a liquid composition comprising a GLP-1 agonist or/and a pharmacologically tolerable salt thereof, an insulin or/and a pharmacologically tolerable salt thereof, and optionally at least one pharmaceutically acceptable adjuvant, the composition being characterised in that it contains methionine, optionally as add-on therapy with metformin. 本发明涉及种包含GLP-1激动剂、胰岛素和甲硫氨酸的药物组合物。具体而言涉及种液体组合物,其包含GLP-1激动剂或/和其药理学可容许盐、胰岛素或/和其药理学可容许盐、和任选地至少种药学可接受赋形剂,其中所述组合物包含甲硫氨酸,在适当情况中作为用二甲双胍的添加疗法。