Fibroin biological scaffold as well as preparation method and application thereof

The invention discloses a fibroin biological scaffold as well as a preparation method and an application thereof. The spinning physiological characteristics of silkworms are changed through a silkworm breeding technology by adopting a wild silkworm variety to obtain the fibroin biological scaffold f...

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Bibliographische Detailangaben
Hauptverfasser: LI SIRU, HE XIAOBAI, BUTAKUZI MULATIBIEKE, ZHANG YESHUN, FANG AI, LIANG PEISHENG, XIA DINGGUO, ZHANG GUOZHENG, WU TANGFENG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a fibroin biological scaffold as well as a preparation method and an application thereof. The spinning physiological characteristics of silkworms are changed through a silkworm breeding technology by adopting a wild silkworm variety to obtain the fibroin biological scaffold for wound healing. The biological scaffold is capable of keeping the natural structure and the activity of fibroin and has the original ecological characteristics of the fibroin. The fibroin biological scaffold has a porous structure and good air permeability and has very high mechanical strength and high biocompatibility. The fibroin biological scaffold has good biocompatibility and cell adhesiveness, is capable of supporting cell survival, proliferation and migration for a long period of time. The fibroin biological scaffold can be applied to an extracellular matrix for supporting cell growth and promoting nutrient exchange, can be used as a medical filling material and can be applied to repairing of multiple tiss