Hypo-sulfonated protein detecting fluorescence probe and preparation method and application thereof

The invention discloses a hypo-sulfonated protein detecting fluorescence probe. The hypo-sulfonated protein detecting fluorescence probe has a following structural formula of (I) and is high in stability, applicable to long-term storage and application and environmentally sensitive. hypo-sulfonated protein detecting fluorescence probe is environmentally sensitive. The hypo-sulfonated protein detecting fluorescence probe is poor in fluorescence in hydrophilic environment and can generate strong fluorescence only after reacting with hypo-sulfonated protein and when fluorophores are located in the hydrophobic environment inside protein structures, so that sulfydryl hypo-sulfonated protein can be developed in situ in cells; meanwhile, the hypo-sulfonated protein detecting fluorescence probe is high in water solubility and large in absorbing and emitting wavelength differential and can extracellularly buffer a solution detecting system and match with tryptophan residues in protein to generate fluorescence resonanc