Carbazolyl-containing chalcone/ethyl acetoacetate Micheal addition product and preparation method thereof
The invention discloses a carbazolyl-containing chalcone/ethyl acetoacetate Micheal addition product and a preparation method thereof. The structural formula is disclosed in the specification. The preparation method comprises the following steps: adding 1-(3-N-substituted-carbazolyl)-3-aryl-acrylket...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses a carbazolyl-containing chalcone/ethyl acetoacetate Micheal addition product and a preparation method thereof. The structural formula is disclosed in the specification. The preparation method comprises the following steps: adding 1-(3-N-substituted-carbazolyl)-3-aryl-acrylketone, sodium hydroxide, ethyl acetoacetate and anhydrous ethanol into a reaction vessel, and carrying out heating under reflux with stirring to perform reaction; and after the reaction finishes, adding a right amount of cold water, carrying out standing for some time until a solid precipitates, carrying out vacuum filtration, repeatedly washing the filter cake with water to a neutral state, carrying out recrystallization with anhydrous ethanol, and carrying out vacuum drying to obtain the target product. The method uses the sodium hydroxide as a catalyst, and adopts a liquid-phase reflux process. The method is simple to operate, and has the advantages of cheap and accessible catalyst, simple after-treatment, high yi |
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