Rotationally isolated translation elements

Provided are nucleic acid translators capable of carrying out logic operations with improved efficiency, maximized output and reduced off-target effects, in particular in a biological system. Methods of using these translators to transduce signal are also provided. 本发明提供能够进行逻辑操作的核酸翻译元件,其具有改善的效率、最大化的...

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Bibliographische Detailangaben
Hauptverfasser: JONATHAN LONG, ZABRAD BOND, GEORGE W FRASER, BRIAN M FURUI, DANIEL J. KLEIBER
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Provided are nucleic acid translators capable of carrying out logic operations with improved efficiency, maximized output and reduced off-target effects, in particular in a biological system. Methods of using these translators to transduce signal are also provided. 本发明提供能够进行逻辑操作的核酸翻译元件,其具有改善的效率、最大化的输出和降低的非靶标效应,特别应用于生物学系统中。本发明还提供了利用这些翻译元件转换信号的方法。