Decellularized pulmonary support and preparation method thereof

The invention provides a decellularized pulmonary support. The decellularized pulmonary support is prepared from sodium lauryl ether sulfate and a DNase I solution through injection treatment. The decellularized pulmonary support prepared by a langendorff injection system is clean in cell removal, a three-dimensional structure and an extracellular matrix protein are reserved completely, and the fusion, cellularization and vascularization are good 6 weeks after allograft subcutaneous transplanting. A preparation method of the decellularized pulmonary support is high in efficiency and simple in step, can be applied to batch production and has a good application prospect in the fields of tissue engineering lungs and loose organs. 本发明提供种脱细胞肺支架，其采用十二烷基醚硫酸钠联合DNase Ⅰ溶液进行灌注处理而成。本发明langendorff灌注系统制备出来的脱细胞肺支架细胞去除干净，三维结构和细胞外基质蛋白保留完整，同种异体皮下移植6周后融合性、细胞化和血管化良好。本发明的制备方法效率高，步骤简单，可以进行量化生产，在组织工程肺及疏松器官领域有良好的应用前景。