Steroid compound and application thereof

The invention discloses a steroid compound and application thereof. The steroid compound is a compound having a structure shown as a formula I or pharmaceutically acceptable salt, tautomer, stereisomer, a precursor compound, hydrate or solvate of the compound (show in the description). An experiment shows that H on the steroid compound C10 having the structure shown as the formula I is substituted by a hydrogen peroxide group, the cardiac muscular tension of the frog heart can be remarkably increased, the steroid compound has a remarkable cardiotonic effect, the cytotoxicity is lower, and the steroid compound is efficient and low in toxicity, can be expected to serve as an active ingredient for preparation of drugs for preventing and/or treating acute heart failure and has a wide application prospect. 本发明公开了种甾体类化合物及其用途，所述甾体类化合物是具有式Ⅰ结构的化合物或所述化合物的药学上可接受的盐、互变异构体、立体异构体、前体化合物、水合物或溶剂化物：实验表明，本发明所述的具有通式Ⅰ结构的甾体类化合物C10上的H被过氧化氢基团取代，可显著增加蛙心的心肌张力，具有显著的强心作用，并且细胞毒性较弱，高效低毒，可望作为活性成分用于制备预防和/或治疗急性心衰的药物，具有广泛的应用前景。