1-phenothiazinyl-3-aryl-3-cyanomethylene-1-acetone and preparation method thereof

The invention provides a 1-phenothiazinyl-3-aryl-3-cyanomethylene-1-acetone and a preparation method thereof. A structural formula of the 1-phenothiazinyl-3-aryl-3-cyanomethylene-1-acetone is shown in the description. During preparation, 1-phenothiazinyl-3-aryl-acrylketone, a catalyst and acetonitri...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: HUANG TAO, YANG XIAOMING, LIU YUTING, YIN DAWEI, XIN HONG, SHENG JIAO, QIAO QIANYU
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention provides a 1-phenothiazinyl-3-aryl-3-cyanomethylene-1-acetone and a preparation method thereof. A structural formula of the 1-phenothiazinyl-3-aryl-3-cyanomethylene-1-acetone is shown in the description. During preparation, 1-phenothiazinyl-3-aryl-acrylketone, a catalyst and acetonitrile are added into a dry mortar and are ground to react, TLC (thin-layer chromatography) tracking and detection are carried out on the reaction until the reaction is complete, washing and suction filtration are then carried out, and after a filter cake is dried, the 1-phenothiazinyl-3-aryl-3-cyanomethylene-1-acetone is obtained. The reaction time in the method is short, a solvent is not needed, the method is environment-friendly and economic, and is easy to operate, the reaction condition is mild, post-processing is simple, and the yield is high. The prepared 1-phenothiazinyl-3-aryl-3-cyanomethylene-1-acetone is a series of brandnew phenothiazinyl-containing ketone derivatives, has effects, such as sterilization and