1-phenothiazinyl-3-aryl-3-cyanomethylene-1-acetone and preparation method thereof
The invention provides a 1-phenothiazinyl-3-aryl-3-cyanomethylene-1-acetone and a preparation method thereof. A structural formula of the 1-phenothiazinyl-3-aryl-3-cyanomethylene-1-acetone is shown in the description. During preparation, 1-phenothiazinyl-3-aryl-acrylketone, a catalyst and acetonitri...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention provides a 1-phenothiazinyl-3-aryl-3-cyanomethylene-1-acetone and a preparation method thereof. A structural formula of the 1-phenothiazinyl-3-aryl-3-cyanomethylene-1-acetone is shown in the description. During preparation, 1-phenothiazinyl-3-aryl-acrylketone, a catalyst and acetonitrile are added into a dry mortar and are ground to react, TLC (thin-layer chromatography) tracking and detection are carried out on the reaction until the reaction is complete, washing and suction filtration are then carried out, and after a filter cake is dried, the 1-phenothiazinyl-3-aryl-3-cyanomethylene-1-acetone is obtained. The reaction time in the method is short, a solvent is not needed, the method is environment-friendly and economic, and is easy to operate, the reaction condition is mild, post-processing is simple, and the yield is high. The prepared 1-phenothiazinyl-3-aryl-3-cyanomethylene-1-acetone is a series of brandnew phenothiazinyl-containing ketone derivatives, has effects, such as sterilization and |
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