1-(3-N-Substituted-carbazoly)-3-aryl-3-(2-oxocyclohexyl)-acetone and preparation method thereof

The invention discloses 1-(3-N-substituted-carbazoly)-3-aryl-3-(2-oxocyclohexyl)-acetone and a preparation method thereof; the 1-(3-N-substituted-carbazoly)-3-aryl-3-(2-oxocyclohexyl)-acetone has a structural formula shown in the description; the preparation method comprises: adding 1-(3-N-substitut...

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Bibliographische Detailangaben
Hauptverfasser: LIU YUTING, LI JIE, YIN DAWEI, XIN HONG, LIU YIJIA, WANG YUWEI, QIAO QIANYU
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses 1-(3-N-substituted-carbazoly)-3-aryl-3-(2-oxocyclohexyl)-acetone and a preparation method thereof; the 1-(3-N-substituted-carbazoly)-3-aryl-3-(2-oxocyclohexyl)-acetone has a structural formula shown in the description; the preparation method comprises: adding 1-(3-N-substituted-carbozoyl)-3-acryl-acetone, NaOH, acetone and absolute ethyl alcohol into a reaction container, stirring and heating for reflux reaction, adding suitable cold water after the reaction, standing for a period of time, when solid separates out, performing suction filtering, washing with water repeatedly until filter cakes are neutral, recrystallizing with absolute ethyl alcohol, evaporating with a rotary evaporator to remove the solvent, and drying in vacuum to obtain the target product. Sodium hydroxide is used herein as a catalyst, and the catalyst has good effect, low in price and easy to obtain; Liquid reflow process is adopted herein, the operation is simple, post-treatment is convenient, the yield is up to 94