Tubular continuous production method of 2, 4-dichloro-5-fluorobenzoyl chloride
The invention provides a tubular continuous production method of 2, 4-dichloro-5-fluorobenzoyl chloride. The method includes: taking 2, 4-dichloro-5-fluoroacetophenone as the starting raw material, performing oxidation on the raw material with oxygen under the catalysis of a mixed acid system of nit...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Patent |
| Sprache: | chi ; eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Zusammenfassung: | The invention provides a tubular continuous production method of 2, 4-dichloro-5-fluorobenzoyl chloride. The method includes: taking 2, 4-dichloro-5-fluoroacetophenone as the starting raw material, performing oxidation on the raw material with oxygen under the catalysis of a mixed acid system of nitric acid and sulfuric acid into 2, 4-dichloro-5-fluorobenzoic acid, then carrying out acylation by bis(trichloromethyl)carbonate (BTC) so as to obtain the final product 2, 4-dichloro-5-fluorobenzoyl chloride. The method provided by the invention adopts a continuous tubular reactor, involves few online reaction materials, and is conducive to DCS control, as a catalyst, nitric acid has a small dosage and can be recycled, oxygen participates in the reaction as an oxidizing agent, and bis(trichloromethyl)carbonate (BTC) substitutes thionyl chloride to serve as an acylation reagent, thus saving cost, and avoiding emission of nitrogen oxides, sulfur dioxide and other harmful gas.
本发明提供了种管式连续化生产2,4-二氯-5-氟苯甲酰氯的制备方法，以2,4-二氯 |
|---|