一种丹曲林钠衍生物及其制备方法

本发明提供了一种丹曲林钠衍生物：2-(((5-(4-硝基苯基)呋喃)-2-亚甲基氨基)-4-氧)-1,4,5-三氢咪唑)-2-氧)-十八碳-9,12-二烯酸乙酯及其制备方法。此丹曲林钠衍生物的结构尚未见文献或专利报道，其合成方法简单，合成条件温和，该分子结构是由丹曲林钠和亚油酸通过乙氧基有机结合在一起，可有效穿过血脑屏障在中枢神经蓄积，达到治疗和预防脑卒中的目的。 The invention relates to a dantrolene sodium derivative: 2-(((5-(4-nitrophenyl)furan)-2-methyleneamino)-4-oxo)-1,4,5-trichloroimidazole)-2-oxo)-octa-9,12-dienoate and a preparation method of the dantrolene sodium derivative. The structure of the dantrolene sodium derivative has not been reported by literatures or patents yet; a synthetic method is simple, and synthetic conditions are mild; the molecular structure is formed by organically bonding dantrolene sodium with ethyoxyl; and the dantrolene sodium derivative can effectively penetrate through blood brain barriers and is accumulated in a central nerve, and therefore, the purposes of treating and preventing cerebral apoplexy are achieved.