Method for preparing high-purity 4-hydroxyethylpiperazine ethanesulfonic acid

The invention belongs to the technical field of preparation of organic matters, and relates to a method for preparing high-purity 4-hydroxyethylpiperazine ethanesulfonic acid. The method sequentially comprises the following specific steps: preparation of 4-hydroxyethylpiperazine ethanesulfonate, aci...

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Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the technical field of preparation of organic matters, and relates to a method for preparing high-purity 4-hydroxyethylpiperazine ethanesulfonic acid. The method sequentially comprises the following specific steps: preparation of 4-hydroxyethylpiperazine ethanesulfonate, acidizing, extraction for decolorizing and removing impurities, reverse extraction, nanofiltration and washing, and drying, so that the high-purity 4-hydroxyethylpiperazine ethanesulfonic acid is finally obtained. The 4-hydroxyethylpiperazine ethanesulfonic acid prepared with the method provided by the invention is high in purity; the operation process is simple and convenient; the production process is environmentally friendly; the purification cost is low; the yield is high; the method is suitable for industrial batch production. 本发明属于有机物制备技术领域,涉及种制备高纯度4-羟乙基哌嗪乙磺酸的方法,具体步骤依次为:4-羟乙基哌嗪乙磺酸盐的制备、酸化处理、萃取脱色和除杂、反萃处理、纳滤以及洗涤、干燥,最终得到高纯度4-羟乙基哌嗪乙磺酸。本发明制得的4-羟乙基哌嗪乙磺酸不仅纯度高,操作工艺简便,而且生产过程环保,纯化成本低,收率高,适合于工业批量生产。