Calcium tablet containing ergosterol and preparation method thereof

The invention discloses a calcium tablet containing ergosterol and a preparation method thereof. The preparation method comprises the following steps: carrying out aerobic fermentation cultivation to saccharomyces cerevisiae by using a optimized culture medium, and improving the expression quantity...

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Bibliographische Detailangaben
Hauptverfasser: AN YUXING, WANG QINGFU, CHEN YINGYING, CHEN RUIRONG, LIANG LEI, BAN WENTING, LI QIWEI, HUANG QINGHUA
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a calcium tablet containing ergosterol and a preparation method thereof. The preparation method comprises the following steps: carrying out aerobic fermentation cultivation to saccharomyces cerevisiae by using a optimized culture medium, and improving the expression quantity of the saccharomyces cerevisiae to the ergosterol; and executing the solid-liquid separation to yeast fermentation liquor, freezing and drying the obtained supernate, to obtain a substance I; after diluting the obtained thallus by using normal saline, executing the solid-liquid separation through the pulsed electric field action, freezing and drying the obtained supernate, to obtain a substance II; mixing the substance I and the substance II, to obtain a substance A; uniformly mixing the substance A, Allah milk calcium, whole milk powder, maltodextrin and a sugarcane extractive, to obtain a mixture; and dissolving the mixture by using the water, spray-drying, pelletizing, drying, size-stabilizing, and tabletting, t