Preparation and application of oxadiazole compound
The invention provides preparation and application of an oxadiazole compound. The preparation method comprises the steps of: adding a first compound and a second compound into a container, and conducting reacting under the action of K2CO3 and THF (Tetrahydrofuran) to obtain a third compound, wherein...
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| creator | WANG LEI YANG CHENG RAO ZIHE LI HUIYING LI JINGPEI LI HUANGONG CHEN YUE SUN TAO BAI CUIGAI GAO YUAN |
| description | The invention provides preparation and application of an oxadiazole compound. The preparation method comprises the steps of: adding a first compound and a second compound into a container, and conducting reacting under the action of K2CO3 and THF (Tetrahydrofuran) to obtain a third compound, wherein the first compound is shown in the description, the second compound is shown in the description, the third compound is shown in the description, and R is selected from groups shown in the description; reacting the third compound under the action of N2H4-H2O and ethanol to obtain a fourth compound, wherein the fourth compound is shown in the description; reacting the fourth compound with a fifth compound under the action of the THF and triethylamine to obtain a sixth compound, wherein the fifth compound is shown in the description, and the sixth compound is shown in the description; reacting the sixth compound under the action of benzene sulfonyl chloride, potassium carbonate and dichloromethane to obtain a seventh |
| format | Patent |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Preparation and application of oxadiazole compound |
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