Preparation and application of oxadiazole compound

The invention provides preparation and application of an oxadiazole compound. The preparation method comprises the steps of: adding a first compound and a second compound into a container, and conducting reacting under the action of K2CO3 and THF (Tetrahydrofuran) to obtain a third compound, wherein...

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Bibliographische Detailangaben
Hauptverfasser: WANG LEI, YANG CHENG, RAO ZIHE, LI HUIYING, LI JINGPEI, LI HUANGONG, CHEN YUE, SUN TAO, BAI CUIGAI, GAO YUAN
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention provides preparation and application of an oxadiazole compound. The preparation method comprises the steps of: adding a first compound and a second compound into a container, and conducting reacting under the action of K2CO3 and THF (Tetrahydrofuran) to obtain a third compound, wherein the first compound is shown in the description, the second compound is shown in the description, the third compound is shown in the description, and R is selected from groups shown in the description; reacting the third compound under the action of N2H4-H2O and ethanol to obtain a fourth compound, wherein the fourth compound is shown in the description; reacting the fourth compound with a fifth compound under the action of the THF and triethylamine to obtain a sixth compound, wherein the fifth compound is shown in the description, and the sixth compound is shown in the description; reacting the sixth compound under the action of benzene sulfonyl chloride, potassium carbonate and dichloromethane to obtain a seventh