Preparation and application of oxadiazole compound
The invention provides preparation and application of an oxadiazole compound. The preparation method comprises the steps of: adding a first compound and a second compound into a container, and conducting reacting under the action of K2CO3 and THF (Tetrahydrofuran) to obtain a third compound, wherein...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention provides preparation and application of an oxadiazole compound. The preparation method comprises the steps of: adding a first compound and a second compound into a container, and conducting reacting under the action of K2CO3 and THF (Tetrahydrofuran) to obtain a third compound, wherein the first compound is shown in the description, the second compound is shown in the description, the third compound is shown in the description, and R is selected from groups shown in the description; reacting the third compound under the action of N2H4-H2O and ethanol to obtain a fourth compound, wherein the fourth compound is shown in the description; reacting the fourth compound with a fifth compound under the action of the THF and triethylamine to obtain a sixth compound, wherein the fifth compound is shown in the description, and the sixth compound is shown in the description; reacting the sixth compound under the action of benzene sulfonyl chloride, potassium carbonate and dichloromethane to obtain a seventh |
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