CORYNEBACTERIUM SP. TRANSFORMED WITH A FRUCTOKINASE GENE DERIVED FROM ESCHERICHIA SP. AND PROCESS FOR PREPARING L-AMINO ACID USING THE SAME

The present invention relates to Corynebacterium sp. that is transformed with an Escherichia sp.-derived fructokinase gene to express fructokinase showing a sufficient activity of converting fructose into fructose-6-phosphate, thereby preventing unnecessary energy consumption, and a method for produ...

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Hauptverfasser: KIM DAEOL, KIM JONGUL, LEE KYUNG-HAN, BAE HYUN-WON, MOON JUN-OK, KIM HYUNG-JOON, BAE HYUN-AE, LIM SANG-JO, JANG JAE-WOO, SUNG JIN-SUCK, KIM TAE-HAN, KIM HYO-JIN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention relates to Corynebacterium sp. that is transformed with an Escherichia sp.-derived fructokinase gene to express fructokinase showing a sufficient activity of converting fructose into fructose-6-phosphate, thereby preventing unnecessary energy consumption, and a method for producing L-amino acids using the strain. The transformed Corynebacterium sp. of the present invention is able to express fructokinase from the Escherichia-derived fructokinase gene to prevent unnecessary energy consumption during fructose metabolism, leading to more cost-effective production of L-amino acids. Therefore, it can be widely used for the effective production of L-amino acids. 本发明涉及转化了埃希氏菌(Escherichia sp.)来源的果糖激酶基因以表达果糖激酶的棒杆菌(Corynebacterium sp.)以及利用该菌株生产L-氨基酸的方法,所述果糖激酶显示出足以将果糖转化为果糖-6-磷酸的活性,从而阻止不必要的能量损耗。本发明的转化的棒杆菌能从埃希氏菌来源的果糖激酶基因表达果糖激酶,以阻止果糖代谢期间不必要的能量损耗,产生更具成本效益的L-氨基酸的生产。因此,其可以被广泛用于有效生产L-氨基酸。