Long wavelength type thiophenol fluorescent probe as well as preparation method and application thereof

The invention discloses a long wavelength type thiophenol fluorescent probe as well as a preparation method and application thereof. According to the long wavelength type thiophenol fluorescent probe, amino porphyrin and 2,4-dinitrobenzenesulfonyl chloride are used as raw materials and proper reacti...

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Hauptverfasser: ZENG RONGJIN, CHEN GUOLIANG, CHENG FENMIN, GAO QIAN, CHEN SHU, LONG YUNFEI, YANG YUNSHAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a long wavelength type thiophenol fluorescent probe as well as a preparation method and application thereof. According to the long wavelength type thiophenol fluorescent probe, amino porphyrin and 2,4-dinitrobenzenesulfonyl chloride are used as raw materials and proper reaction conditions are controlled to obtain a target probe compound. The fluorescent probe disclosed by the invention has a very long fluorescence emission wavelength (lambda-em is more than 650nm), rapid response and high anti-interference capability; high-selectivity and high-sensitivity fluorescent recognition and detection on trace thiophenol in a water environment and a biological sample can be realized; the long wavelength type thiophenol fluorescent probe has very good application prospect. 本发明公开了种长波型的苯硫酚荧光探针及制备方法和应用。本发明以氨基卟啉和2,4-二硝基苯磺酰氯为原料,通过控制适宜的反应条件获得目标探针化合物。本发明的荧光探针具有很长的荧光发射波长(λ﹥650nm),响应快速,抗干扰能力强,可实现对水环境和生物样品中微量苯硫酚高选择性和高灵敏度的荧光识别和检测,具有很好的应用前景。