Preparation of controlled release skeletal muscle relaxant dosage forms

The present invention is directed to a method of preparing an extended release pharmaceutical composition comprising cyclobenzaprine, comprising coating inert particles with a cyclobenzaprine-containing the drug layering composition and a seal coating composition to form IR beads, then coating the I...

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Bibliographische Detailangaben
Hauptverfasser:	VENKATESH GOPI, CLEVEGER JAMES M, GRINSTEAD TIMOTHY
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention is directed to a method of preparing an extended release pharmaceutical composition comprising cyclobenzaprine, comprising coating inert particles with a cyclobenzaprine-containing the drug layering composition and a seal coating composition to form IR beads, then coating the IR beads with an extended release coating to form ER beads. 本发明是针对制备种包括环苯扎林的延长释放药物组合物的种方法，包括用种含有环苯扎林的药物层组合物对惰性颗粒进行包被以形成IR珠粒，然后用种延长释放包衣对这些IR珠粒进行包被以形成ER珠粒。