Anti-HIV compound preparation and preparation method and application thereof

The invention discloses anti-HIV compound preparation. The anti-HIV compound preparation is prepared from the following ingredients in weight percentage: 10 to 35% of lamivudine, 10 to 35% of fumaric acid tenofovir ester, 5 to 20% of 3-((3-ethyl-2,6-dioxo-5-(propyl-2-radical)-1,2,3,6-tetrahydropyrimidine-4-radical)carbonyl)-5-tolunitrile and 10 to 75% of excipient. The anti-HIV compound preparation disclosed by the invention is single-layer tablet or double-layer tablet; in preparation, the fumaric acid tenofovir ester and compound of the 3-((3-ethyl-2,6-dioxo-5-(propyl-2-radical)-1,2,3,6-tetrahydropyrimidine-4-radical)carbonyl)-5-tolunitrile are independently pelletized and then totally mixed and compressed into tablets. The anti-HIV compound preparation disclosed by the invention has the advantages of good stability, a simple preparation technology and controllable quality, can restrain HIV virus from different targets, improves a treating effect of single drug use to AIDS, avoids side effects on a nervous