Sildenafil citrate smell masking resin compound and application thereof
The invention discloses a sildenafil citrate smell masking resin compound and application thereof, and aims at solving the technical problems to shield the bad smell of the medicine active ingredient of sildenafil citrate, so that good mouthfeel can be realized. The medicine smell masking resin comp...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses a sildenafil citrate smell masking resin compound and application thereof, and aims at solving the technical problems to shield the bad smell of the medicine active ingredient of sildenafil citrate, so that good mouthfeel can be realized. The medicine smell masking resin compound is prepared from sildenafil citrate and acid type cation exchange resin through a static exchange method; the weight ratio of the sildenafil citrate to the acid type cation exchange resin is 0.5:1 to 3:1. The prepared sildenafil citrate smell masking resin compound can be further prepared into chewable tablets, orally disintegrating tablets, granules and suspensions. Compared with the prior art, the sildenafil citrate smell masking resin compound has the advantages that an ion exchange technology is used; the bad smell of the sildenafil citrate can be effectively shielded; the patient compliance is improved; the preparation process is simple; the sildenafil citrate smell masking resin compound is suitable for |
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