Anti-myocardial fibrosis traditional Chinese medicine compound

The invention discloses an anti-myocardial fibrosis traditional Chinese medicine compound. The crude drugs of the active ingredients include peach kernel, red flower, red peony root, ligusticum wallichii and achyranthes bidentata. The anti-myocardial fibrosis traditional Chinese medicine compound pr...

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Hauptverfasser:	LYU LIN, YANG GUANG, SUI YUKUN, CHEN KAI, ZHOU LEI, ZHANG YUBIN, TIAN NANNAN, LIU XIN, GAO MINGLONG, WU SHAOYU, JI YUHENG, ZHOU XIAOLI, TAN SHAOBIN, DANG WENZHEN, ZHUANG YUXIN, ZHANG GUOHUA
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention discloses an anti-myocardial fibrosis traditional Chinese medicine compound. The crude drugs of the active ingredients include peach kernel, red flower, red peony root, ligusticum wallichii and achyranthes bidentata. The anti-myocardial fibrosis traditional Chinese medicine compound provided by the invention has the following beneficial effects: an in vivo experiment result proves that the traditional Chinese medicine compound can improve the ejection fraction of myocardial fibrosis rate, the shortening fraction effect is optimal and the therapeutic effect is better than that of xuefu zhuyu decoction and captopril; an ex vivo experiment result proves that the traditional Chinese medicine compound provided by the invention can exert the anti-myocardial fibrosis function by restraining the expressions of cardiac muscle fiber cells Col I, Col III and alpha-SMA expression and the therapeutic effect is better than that of xuefu zhuyu decoction and Western medicine captopril; relative to the other com