ORAL DOSAGE FORM

The present invention is in the field of delivering an active substance to the oral cavity and relates to mucoadhesive active composition and corresponding mucoadhesive dosage form, which can deliver an active substance within the oral cavity, especially an orodispersible tablet for delivering probi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GOTZ MARCUS RUDOLF, DANIELS, ROLF, HOLMGREN, KERSTIN, HOFFMANN, ANJA, FISCHER JORG THILO
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention is in the field of delivering an active substance to the oral cavity and relates to mucoadhesive active composition and corresponding mucoadhesive dosage form, which can deliver an active substance within the oral cavity, especially an orodispersible tablet for delivering probiotic substance. The present invention also relates to a method of producing the said composition and a method of processing the composition into a mucoadhesive dosage form, especially an orodispersible tablet. The present invention moreover relates to a system and a method for testing the mucoadhesion of a dosage form. 本发明属于向口腔输送活性物质的领域,并且涉及粘膜粘附活性组合物以及相应的粘膜粘附剂型,其可以在口腔内释放活性物质,尤其是用于输送益生菌物质的口腔分散片。本发明还涉及种生产所述组合物的方法以及种将该组合物加工为粘膜粘附剂型,尤其是口腔分散片的方法。此外本发明涉及种测试剂型粘膜粘附性能的系统和方法。