Novel withanolide compound as well as preparation method and medicinal application thereof

The invention discloses a novel withanolide compound as well as a preparation method and medicinal application thereof, belongs to the field of medicines, and in particular relates to a novel withanolide compound which is separated from dried eucommia ulmoides oliv. leaves, and a preparation method...

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1. Verfasser: ZHANG SHENGTI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a novel withanolide compound as well as a preparation method and medicinal application thereof, belongs to the field of medicines, and in particular relates to a novel withanolide compound which is separated from dried eucommia ulmoides oliv. leaves, and a preparation method and medicinal application of the novel withanolide compound. The novel withanolide compound is reported for a first time, can be obtained through extraction and separation from dried eucommia ulmoides oliv. Leaves and purification, and is high in purity. In-vitro tests show that the compound is capable of inhibiting SAH (S-Adenosyl-L-homocysteine hydrolase) hydrolytic enzyme activity, has antiviral activity and can be applied to the antiviral field to prepare antiviral medicines. 本发明公开了种新的醉茄内酯类化合物及其制备方法和医药用途,属于药物领域,具体涉及从干燥的杜仲叶中分离得到的种新的醉茄内酯类化合物及其制备方法和医药用途。该化合物为首次报道,可以从干燥的杜仲叶中提取、分离纯化得到,纯度高。体体外试验证明该化合物能抑制SAH水解酶活性,具有抗病毒的活性,可以将该化合物应用于抗病毒领域,制备抗病毒药物。