Haemophilus parasuis tetravalent inactivated vaccine
The invention provides a haemophilus parasuis tetravalent inactivated vaccine, wherein antigens are inactivated haemophilus parasuis YBH04, YBH05, YBH12 and YBH13 strains. The collection number of a type-4 YBH04 strain is CGMCC No. 5479, the collection number of a type-5 YBH05 strain is CGMCC No. 54...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention provides a haemophilus parasuis tetravalent inactivated vaccine, wherein antigens are inactivated haemophilus parasuis YBH04, YBH05, YBH12 and YBH13 strains. The collection number of a type-4 YBH04 strain is CGMCC No. 5479, the collection number of a type-5 YBH05 strain is CGMCC No. 5480, the collection number of a type-12 YBH12 strain is CCTCC M 2016636, and the collection number of a type-13 YBH13 strain is CGMCC No. 5501. According to the invention, the type-4 YBH04 strain, the type-5 YBH05 strain, the type-12 YBH12 strain and the type-13 YBH13 strain of the haemophilus parasuis, having good immunogenicity, are screened from dominant popular strains to serve as strains for preparing the vaccine, and are inoculated to a TSB (Tryptone Soya Broth) nutrient broth medium respectively for cultivation, cultures are harvested and are inactivated by a formaldehyde solution, and a 201 adjuvant is added for mixed emulsification so as to prepare the vaccine. The haemophilus parasuis tetravalent inactivat |
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