Haemophilus parasuis tetravalent inactivated vaccine

The invention provides a haemophilus parasuis tetravalent inactivated vaccine, wherein antigens are inactivated haemophilus parasuis YBH04, YBH05, YBH12 and YBH13 strains. The collection number of a type-4 YBH04 strain is CGMCC No. 5479, the collection number of a type-5 YBH05 strain is CGMCC No. 54...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: GUO LILI, GONG XIAO, LIU XINWEN, HU XIAO, SHEN HONGYIN
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention provides a haemophilus parasuis tetravalent inactivated vaccine, wherein antigens are inactivated haemophilus parasuis YBH04, YBH05, YBH12 and YBH13 strains. The collection number of a type-4 YBH04 strain is CGMCC No. 5479, the collection number of a type-5 YBH05 strain is CGMCC No. 5480, the collection number of a type-12 YBH12 strain is CCTCC M 2016636, and the collection number of a type-13 YBH13 strain is CGMCC No. 5501. According to the invention, the type-4 YBH04 strain, the type-5 YBH05 strain, the type-12 YBH12 strain and the type-13 YBH13 strain of the haemophilus parasuis, having good immunogenicity, are screened from dominant popular strains to serve as strains for preparing the vaccine, and are inoculated to a TSB (Tryptone Soya Broth) nutrient broth medium respectively for cultivation, cultures are harvested and are inactivated by a formaldehyde solution, and a 201 adjuvant is added for mixed emulsification so as to prepare the vaccine. The haemophilus parasuis tetravalent inactivat