Insulin glargine injection and preparation method thereof

The invention belongs to the technical field of medicines, and provides an insulin glargine injection and a preparation method. The insulin glargine injection consists of insulin glargine, glycerin, methylparaben, zinc chloride, sodium pyrosulfite, a pH adjusting agent and injection water. The insulin glargine injection provided by the invention is injected into an ampoule bottle, a formula is adjusted by the inventor, the problem that the appearance and the morphology of the injection are changed because of high-temperature melting sealing in the filling process of the ampoule bottle can be overcome, and the risk that the insulin glargine injection is turbid because of high temperature can be avoided. 本发明属于医药技术领域，提供了种甘精胰岛素注射液，由甘精胰岛素、甘油、羟苯甲酯、氯化锌、焦亚硫酸钠、PH调节剂和注射用水组成。本发明注射液采用安瓿瓶灌装，发明者通过对处方的调整，克服了安瓿瓶在灌装过程由于高温熔封造成注射液外观性状改变的问题，避免了甘精胰岛素注射液由于高温出现浑浊的风险。