Favipiravir tablets and preparation method thereof

The invention relates to favipiravir tablets. The tablets comprise favipiravir, silicified microcrystalline cellulose and adhesive; the silicified microcrystalline cellulose is lower in price, proper in size and high in medicine compliance when being compared with low-substituted hydroxypropyl cellu...

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Bibliographische Detailangaben
Hauptverfasser: ZHANG WEILING, LIU YONGJIN, LIU CUIYAN, ZHANG YUANYUAN, ZHANG HONGFEN, BU LICHAO, BAI JING
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention relates to favipiravir tablets. The tablets comprise favipiravir, silicified microcrystalline cellulose and adhesive; the silicified microcrystalline cellulose is lower in price, proper in size and high in medicine compliance when being compared with low-substituted hydroxypropyl cellulose; the defective rate is lower and the dissolution rate is higher. The invention further relates to a preparation method of the tablets. The preparation method is simple in preparation process and suitable for industrialized large-scale production. 本发明涉及种法匹拉韦片剂,该片剂含有法匹拉韦、硅化微晶纤维素和粘合剂,采用硅化微晶纤维素相对于低取代羟丙基纤维素,价格更加低廉、大小合适、药物顺应性良好,并且次品率更低和溶出更好。本发明还涉及所述片剂的制备方法,该制备方法制备工艺简单,适合工业化大生产。