Durable preparation of an injectable of melatonin exhibiting long-term stability

The invention relates to an aqueous composition of melatonin exhibiting surprising long-term stability and allowing high concentrations of said water-insoluble active ingredient. The properties of said composition render it useful as an injectable, for example, for the intravenous administration the...

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Hauptverfasser: FERRON ORIHUELA JOSE ANTONIO, VENEGAS MALDONADO CARMEN, BUENO LARANO PABLO, GONZALEZ CALLEJAS DESIREE, OLMEDO MARTIN CARMEN, ACUNA CASTROVIEJO DARIO, HERNANDEZ MAGDALENA JOSE JORGE, MANSILLA ROSELLO ALFONSO, CALLEJA HERNANDEZ MIGUEL ANGEL, COMINO PARDO ANA, ESCAMES ROSA GERMAINE
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to an aqueous composition of melatonin exhibiting surprising long-term stability and allowing high concentrations of said water-insoluble active ingredient. The properties of said composition render it useful as an injectable, for example, for the intravenous administration thereof. 本发明涉及种呈现惊人的长期稳定性和允许高浓度的所述水不溶性活性成分的水性褪黑素组合物。所述组合物的性质使其可用作注射剂,例如用于静脉内给药。