Method for establishing fingerprint of lame impediment treating pills and method for identifying lame impediment treating pills by using fingerprint method

The invention relates to a method for establishing a fingerprint of lame impediment treating pills. The method comprises the steps of obtaining chromatograms of the lame impediment treating pills of different production batches by adopting high-performance liquid chromatography, selecting a chromato...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GAO YUNJIA, ZHANG WENTAO, QIN PEIHONG, TU PENGFEI, ZHENG JIYU, GUO YAN, LI WEILI, WANG YANMIN, SUN YUNCHAO, ZHOU SHUFAN
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention relates to a method for establishing a fingerprint of lame impediment treating pills. The method comprises the steps of obtaining chromatograms of the lame impediment treating pills of different production batches by adopting high-performance liquid chromatography, selecting a chromatographic peak, which is present in the chromatograms of the lame impediment treating pills of all the batches, as a common peak, and generating the fingerprint of the lame impediment treating pills by using an average value computation method, wherein a stationary phase is octadecylsilane chemically bonded silica, an organic phase of a flowing phase is acetonitrile, and a water phase is an aqueous solution of phosphoric acid. The invention further relates to a method for identifying the lame impediment treating pills by using a fingerprint method. According to the method provided by the invention, the comprehensive monitoring on drug quality is facilitated, the sequential order and mutual relationship of all charact