Method for improving chorionic gonadotrophin titer

The invention discloses a method for purifying chorionic gonadotrophin. The technology is capable of using three times of chromatography to purify the chorionic gonadotrophin of low titer, and purifying the chorionic gonadotrophin from about 300 IU/mg of the titer to about 9000 IU/mg of the titer. The titer is greatly improved and other quality standards accord with each index specified by Chinese Pharmacopoeia, United States Pharmacopeia and European Pharmacopoeia. The method has the advantages of simpliness, high product purity and yield, and low cost, and is suitable for large-scale industrial production of the pharmaceuticals industry. 本发明公开了种绒促性素纯化的方法，该技术运用三次层析纯化低效价绒促性素，将效价约为300IU/mg的绒促性素纯化为9000IU/mg左右，效价显著提高，其它质量标准符合中国药典、美国药典及欧洲药典所规定的各项指标，本发明方法具有简单、产品纯度和收率高、成本低等优点，适合医药行业大规模工业生产。