Disulfide derivative containing 1,3,4-oxa(thia)diazole and preparation method and application of derivative

The invention discloses a disulfide derivative containing 1,3,4-oxa(thia)diazole and a preparation method and application of the derivative. The disulfide derivative has the following general formula (as shown in the specification), wherein R1 is selected from 4-chlorphenyl, 4-fluoro-phenyl, benzyl,...

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Hauptverfasser: LI MINGWEI, LI XIANGYANG, TIAN PINGYI, ZHOU DAGUI, YI CHONGFEN, ZENG SONG, YANG SONG, HE WU, WANG YANJIAO, SONG BAO'AN, CHEN JIXIANG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a disulfide derivative containing 1,3,4-oxa(thia)diazole and a preparation method and application of the derivative. The disulfide derivative has the following general formula (as shown in the specification), wherein R1 is selected from 4-chlorphenyl, 4-fluoro-phenyl, benzyl, 4-chloro-benzyl and other substituent groups; R2 is selected from methyl, ethyl, benzyl, 4-chloro-benzyl, ethyl acetate and other substituent groups; X is O or S. The disulfide derivative disclosed by the invention can serve as a medicine or agent for killing nematodes and inhibiting crop bacterium diseases. 本发明公开了种含1,3,4-噁(噻)二唑的双硫醚类衍生物、其制备方法及应用,其通式如下:(I)其中:R选自4-氯苯基、4-氟苯基、苄基及4-氯苄基等取代基;R选自甲基、乙基、苄基、4-氯苄基及乙酸乙酯等取代基;X为O或S。本发明可用作杀线虫和抑制作物细菌性病的药物或药剂。