Novel quinoline derivatives and their use in neurodegenerative diseases

The present invention relates to quinoline compounds, and pharmaceutically acceptable compositions thereof, useful as antagonists of P2X7, and for the treatment of P2X7-related disorders. 本发明涉及喹啉化合物及其药学上可接受的组合物，它们可用作P2X7拮抗剂，用于治疗与P2X相关的疾病或病症。...

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Bibliographische Detailangaben
Hauptverfasser:	JAYADEVAN JAYASHANKARAN, XIAO YUFANG, KARRA SRINIVASA R, SEENISAMY JEYAPRAKASHNARAYANAN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to quinoline compounds, and pharmaceutically acceptable compositions thereof, useful as antagonists of P2X7, and for the treatment of P2X7-related disorders. 本发明涉及喹啉化合物及其药学上可接受的组合物，它们可用作P2X7拮抗剂，用于治疗与P2X相关的疾病或病症。