Preparation method of cefoxitin sodium powder-needle preparation for injection

The invention discloses a preparation method of a cefoxitin sodium powder-needle preparation for injection, and belongs to the technical field of medicine. The preparation method comprises: (1) preparing a sterile sodium forming agent solution; (2) preparing a sterile cefoxitin solution so as to be spare; (3) crystallizing and drying; and (4) sub-packaging the preparation according to different specifications. The invention provides the preparation method of the cefoxitin sodium powder-needle preparation for injection, wherein the prepared cefoxitin sodium powder-needle preparation has advantages of high purity, uniform particle size distribution, high color grade, high clarity, good medicinal effect, high income, high stability and the like by improving the crystallization process. 本发明公开了种注射用头孢西丁钠粉针制剂的制备方法，属于医药技术领域，包括以下几个步骤：步骤（1），制备无菌成钠剂溶液备用；步骤（2），制备无菌头孢西丁酸溶液备用；步骤（3），结晶、干燥；步骤（4），不同规格制剂分装。本发明提供种注射用头孢西丁钠粉针制剂的制备方法，通过改进结晶工艺使制备的头孢西丁钠粉针制剂具备纯度高、粒度分布均匀、色级、澄清度高、药用效果好、收益高、稳定性高等优势。