Novel N-isopropyl-benzamide compound for adjusting activity of estrogen-related receptor and medical application of novel N-isopropyl-benzamide compound
The invention discloses a novel N-isopropyl-benzamide compound (with a formula I) for adjusting activity of an estrogen-related receptor, medical acceptable salt of the novel N-isopropyl-benzamide compound and an application of the novel N-isopropyl-benzamide compound. The compound and the medical a...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses a novel N-isopropyl-benzamide compound (with a formula I) for adjusting activity of an estrogen-related receptor, medical acceptable salt of the novel N-isopropyl-benzamide compound and an application of the novel N-isopropyl-benzamide compound. The compound and the medical acceptable salt of the compound can be used for preparing drugs capable of adjusting the activity of the estrogen-related receptor ERR-alpha (Estrogen-related receptor alpha, ERR-alpha or ERR alpha) and preventing and curing the breast cancer, the prostatic cancer, the stomach cancer, the colon cancer, the ovarian cancer, the cervical cancer and other malignant tumors.
本发明公开了种具有式I的新型N-异丙基-苯甲酰胺类调节雌激素相关受体活性的化合物及其药学上可接受的盐及其应用。该化合物及其药学上可接受的盐可用于制备具有调节雌激素相关受体ERR-alpha(Estrogen-related receptor alpha,ERR-alpha或ERRα)活性,预防和治疗乳腺癌、前列腺癌、胃癌、结肠癌、卵巢癌、宫颈癌等恶性肿瘤的药物。 |
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