Dextromethorphan hydrobromide orally disintegrating tablet and preparation method thereof

The invention discloses a dextromethorphan hydrobromide orally disintegrating tablet, which comprises dextromethorphan hydrobromide and auxiliary materials. The auxiliary materials are selected from one or more of beta-cyclodextrin, mannitol, microcrystalline cellulose, magnesium stearate, crosslink...

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Bibliographische Detailangaben
Hauptverfasser: ZHANG GUOFENG, XU MINGKAI, LI YUEYUE, ZHANG WENJUN, LYU BAOGUANG, WANG SONG
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention discloses a dextromethorphan hydrobromide orally disintegrating tablet, which comprises dextromethorphan hydrobromide and auxiliary materials. The auxiliary materials are selected from one or more of beta-cyclodextrin, mannitol, microcrystalline cellulose, magnesium stearate, crosslinked polyvinylpyrrolidone, aspartame, sodium carboxymethylcellulose, lactose, starch, glyceryl behenate, crosslinked carboxymethyl starch and lauryl sodium sulfate. Compared with the prior art, the dextromethorphan hydrobromide orally disintegrating tablet provided by the invention has shorter disintegration time and better taste than traditional tablets and capsules, can rapidly disintegrate and dissolve out in an oral cavity without the need for taking with water, takes effect rapidly, and can be conveniently taken by the aged, the children and patients with difficulty in taking medicine, and the effectiveness, the safety and the compliance of a medicine are improved. A preparation method adopts common equipment, a