Alantolactone derivative and application of derivative salt to preparation of drugs for treating inflammatory bowel diseases

The invention provides an alantolactone derivative and an application of derivative salt to preparation of drugs for treating inflammatory bowel diseases. The alantolactone derivative is as shown in a formula (I-II) or (I-III). According to the alantolactone derivative, acid forming the salt is inor...

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Bibliographische Detailangaben
Hauptverfasser: YANG GUANG, ZHOU HONGGANG, BI ZHUN, ZHAO YONGLE, YIN CHUNXIAO, HOU JIANNAN, ZHANG HONGDAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides an alantolactone derivative and an application of derivative salt to preparation of drugs for treating inflammatory bowel diseases. The alantolactone derivative is as shown in a formula (I-II) or (I-III). According to the alantolactone derivative, acid forming the salt is inorganic acid or organic acid, the inorganic acid is selected from hydrofluoric acid, hydrochloric acid, hydrobromic acid, hydroiodic acid, sulfuric acid, nitric acid, phosphoric acid, carbonic acid, boracic acid, seleninic acid, phosphomolybdic acid, phosphorous acid and sulfurous acid, the organic acid is selected from citric acid, maleic acid, D-malic acid, L-malic acid, DL-malic acid, L-lactic acid, D-lactic acid, DL-acid, oxalic acid, methanesulfonic acid, valeric acid, oleic acid, lauric acid, p-toluene sulfonic acid, 1-naphthalene sulfonic acid, 2-naphthalene sulfonic acid, phthalic acid, tartaric acid, malonic acid, succinic acid, fumaric acid, glycollic acid, thioglycollic acid, glycine, sarcosine, sulfonic a