Device and method to treat or prevent joint degeneration

A method for the delivery of aggrecan precursors to the joint of a subject, comprising the steps of: a) applying a composition comprising one or more aggrecan precursors chosen from the list comprising hyaluronic acid, glucosamine sulfate and/or chondroitin sulfate to the skin of the subject on or near a joint, wherein the composition is applied between the skin and a flexible magnetic film. 种用于向受试者的关节递送聚集蛋白聚糖前体的方法，其包括以下步骤：a)将包含种或多种选自列表的聚集蛋白聚糖前体的组合物施用到所述受试者关节上或关节附近的皮肤，所述列表包括透明质酸、硫酸葡萄糖胺和/或硫酸软骨素，其中所述组合物施用在皮肤与柔性磁膜之间。