Histone acetyltransferase modulators and uses thereof

The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject. 本发明提供调节组蛋白酰基转移酶(HAT)的化合物和包含所述化合物的组合物。本发明另外提供用于通过向受试者施用调节HAT的化合物来治疗神经退行性病症、与累积的淀粉样蛋白-β肽沉积物、τ蛋白水平和/或α-突触核蛋白的累积相关的病状以及癌症的方法。