METHODS AND COMPOSITIONS FOR THE DELIVERY OF A THERAPEUTIC AGENT

The present invention provides a liquid pharmaceutical composition comprising a therapeutic agent and an alkoxy-polyethylene glycol, for example, methoxy-polyethylene glycol, for administration of the therapeutic agent to the mammal. The compositions can be applied to a membrane, for example, a nasa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GIZURARSON SVEINBJORN, YAZDI MEHDI, GHADERI RAOUF, LUSTY MICHAEL E, ARP JAMES, PLUCINSKI GREGORY G
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The present invention provides a liquid pharmaceutical composition comprising a therapeutic agent and an alkoxy-polyethylene glycol, for example, methoxy-polyethylene glycol, for administration of the therapeutic agent to the mammal. The compositions can be applied to a membrane, for example, a nasal membrane during intranasal administration. The invention also provides methods of administering such compositions to a mammal. 本申请提供种液体药物组合物,包含治疗剂和烷氧基-聚乙二醇,例如甲氧基-聚乙二醇,用于将治疗剂施用于哺乳动物。该组合物可以应用于膜,例如在鼻内施用期间用于鼻膜。本发明也提供将该组合物施用于哺乳动物的方法。