Preparation method for multilayer lipid vesicles packaging forskolin

The invention relates to a preparation method for multilayer lipid vesicles packaging forskolin. The preparation method is characterized by including the steps of 1), weighing the forskolin and water-soluble alcohol prior to mixing to obtain forskolin alcohol dispersion liquid; 2), weighing polyglycerol-10 stearate, glycerin monostearate and glyceryl stearate citrate prior to mixing to obtain a nonionic surfactant mixture; 3), weighing 10-30% of the forskolin alcohol dispersion liquid, 1-25% of the nonionic surfactant mixture, 0.5-12% of hydrogenated lecithin and deionized water; 4), dissolving the hydrogenated lecithin in the deionized water to obtain a hydrogenated lecithin water solution; 5), under the assistance of 50-100 KHZ (kilohertz) ultrasonic wave, adding the nonionic surfactant mixture and the hydrogenated lecithin water solution into the forskolin alcohol dispersion liquid, controlling the ultrasonic temperature to be 70-80DEGC, maintaining for 5-30 minutes, and cooling to obtain the multilayer li