Gold-plated nanorod and preparation method and application thereof

The invention discloses a gold-plated nanorod and a preparation method and application thereof. The gold-plated nanorod is obtained by wrapping a gold nanorod in an erythrocyte membrane of human beings or animals. The obtained gold nanorod wrapped by the erythrocyte membrane is good in wrapping and...

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Bibliographische Detailangaben
Hauptverfasser: JIANG TING, HU YU, PANG ZHIQING, MEI HENG, SHI WEI, WEI QIUZHE
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a gold-plated nanorod and a preparation method and application thereof. The gold-plated nanorod is obtained by wrapping a gold nanorod in an erythrocyte membrane of human beings or animals. The obtained gold nanorod wrapped by the erythrocyte membrane is good in wrapping and stability and has the good photothermal conversion characteristic and biocompatibility, tumor diagnosing and real-time monitoring can be achieved through photoacoustic imaging according to the characteristics that the circulating time of blood in animal bodies is long, and the targeted accumulation content in tumors is high, local temperature increasing of the tumors can be achieved through near-infrared light irradiation, tumor growth is inhibited in the bodies, and the survival rate of the animals is increased. 本发明公开了种包金纳米棒、其制备方法及其应用,本发明的包金纳米棒由人或动物的红细胞膜包被金纳米棒所得。本发明获得的红细胞膜包金纳米棒包裹良好,稳定性好,具有优良的光热转换特性及生物相容性,动物体内血液中循环时间长、肿瘤中靶向蓄积含量高的特点,可通过光声成像实现肿瘤诊断和实时监测,可通过近红外光线照射实现肿瘤局部升温,在体内抑制肿瘤生长、提高动物存活率。