Solid pharmaceutical composition containing compound A and preparing method thereof

The invention discloses a solid pharmaceutical composition containing a compound A. The weight percentage of an impurity E in the solid pharmaceutical composition is not larger than 1.0%, and the weight percentage of water is 2.5-7%. The solid pharmaceutical composition is high in stability, so that...

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Bibliographische Detailangaben
Hauptverfasser: YE GUANHAO, ZHI JIANQIONG, DENG YUN, XU WENJIE
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention discloses a solid pharmaceutical composition containing a compound A. The weight percentage of an impurity E in the solid pharmaceutical composition is not larger than 1.0%, and the weight percentage of water is 2.5-7%. The solid pharmaceutical composition is high in stability, so that drug using safety and effectiveness are effectively guaranteed. Meanwhile, adverse reaction generated during usage of the pharmaceutical composition is reduced, product quality is effectively guaranteed, and drug using safety and effectiveness are well guaranteed. 本发明公开了种含有化合物A的固体药物组合物,该固体药物组合物中的杂质E重量百分含量不超过1.0%,且水分重量百分含量在2.5-7.0%范围内。本发明提供的固体药物组合物,稳定性良好,从而有效地保证了药物使用的安全性及有效性。同时降低了药物组合物使用过程中不良反应的发生,有效地保证了产品的质量,对用药安全性和有效性提供了良好的保障。