Immunoglobulin purification using pre-cleaning steps

The present invention relates to the purification of immunoglobulins and the problem of providing a method for purifying an immunoglobulin in an efficient and cost-effective manner and with satisfactory purity and yield. In particular, the present invention addresses the aspect of the re-use of the rather cost-intensive chromatography materials, in particular the lifetime of the chromatography materials used in the capture step of the downstream process, and how this can be increased while reducing the technical complexity of the purification process. 本发明涉及免疫球蛋白的纯化，及提供用于以有效而节约成本的方式和以令人满意的纯度和产率纯化免疫球蛋白的方法的问题。具体而言，本发明涉及成本非常高的层析材料的重复利用方面，尤其是用于下游工艺捕获步骤的层析材料的寿命，及可以如何在降低纯化工艺技术复杂性的同时增加层析材料寿命。