Micelle containing bubbles for drug delivery and method for manufacturing same

Disclosed are a micelle containing bubbles for drug delivery and a method for manufacturing the same. The micelle formed according to the present invention includes micro-bubbles formed by evaporating the liquefied inert gas due to the irradiation of ultrasonic waves to a solution in which the lique...

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Bibliographische Detailangaben
Hauptverfasser: SEO JONG BUM, WON JONG HO, SONG GILL SOO, PARK JIN KAM, KIM SUNG BAE, SHIN UN CHOL, SON JUNG WOO
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Disclosed are a micelle containing bubbles for drug delivery and a method for manufacturing the same. The micelle formed according to the present invention includes micro-bubbles formed by evaporating the liquefied inert gas due to the irradiation of ultrasonic waves to a solution in which the liquefied inert gas is mixed with a drug for disease treatment, and the micelle is formed as a unit structure in which the micro-bubbles are contained in a cavity and the cavity is enclosed in a shell, and delivers the drug to the human body. Therefore, the micelle can protect a material of the drug, which is delivered to the human body, as well as deliver a larger amount of the drug than the existing technique, and can be easily applied to the treatment of various diseases. 本发明公开了用于给药的包括气泡的胶团及其制备方法。根据本发明形成的胶团(micelle)包括微气泡(microbubble),该微气泡是通过向由液化惰性气体和用于治疗疾病的药物混合而成的溶液中照射超声波以使液化惰性气体气化而形成的,其中,所述胶团在内部以腔(cavity)的形状包含微气泡,并具有由膜(shell)包围的单位结构,以将药物递送到人体。因此,不仅能够传递比以往更多的量的药物,而且能够保护传递到人体的药物的物质,并且能够容易地适用于各种疾病的治疗。