Extraction method of nosiheptide

The invention relates to an extraction method of nosiheptide. The extraction method comprises the following process steps: nosiheptide fermentation liquid atomizing and drying, composite solvent extraction and centrifugation, macroporous resin absorption, acid water hydrolysis, brine precipitation, washing, depressurization and drying. The invention provides a process for extracting the nosiheptide by utilizing composite solvent extraction and macroporous resin de-coloration and purification. According to the method provided by the invention, the extraction efficiency can be improved by 6.5 percent or more, the product purity reaches 96 percent or above, and the economic benefits are favorably improved. According to the method provided by the invention, the wastewater discharge amount is reduced, and the environmental protection treatment is facilitated. The extraction method provided by the invention has the benefits that the solvent corrosion is low, the toxicity is low, the equipment maintenance is facilit