Electrochemical catalysis synthesis method of 3-sulfonyl substituted oxo indoles compound

The invention discloses an electrochemical catalysis synthesis method of a 3-sulfonyl substituted oxo indoles compound, and belongs to synthesis of compounds. The method uses a sulfoacid reagent represented by a formula (III) or sulfonyl hydrazine represented by a formula (V) or N-substituted acryla...

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Hauptverfasser: ZENG CHENGCHU, HU LIMING, JIANG YANGYE
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses an electrochemical catalysis synthesis method of a 3-sulfonyl substituted oxo indoles compound, and belongs to synthesis of compounds. The method uses a sulfoacid reagent represented by a formula (III) or sulfonyl hydrazine represented by a formula (V) or N-substituted acrylamide represented by a formula (II) as a raw material in a single-cell electrolytic tank; and in presence of an electrocatalyst, the raw material is electrolyzed in electrolyte at a certain temperature to obtain the 3-sulfonyl substituted oxo indoles compound represented by a formula (I). The method firstly adopts an operation-simple electrochemical catalysis indirect electrolysis method to synthesize the 3-sulfonyl substituted oxo indoles compound, uses the single-cell electrolytic tank and constant-current electrolysis, uses a cheap and easy-obtained graphite piece as a working electrode, largely reduces the cost, in particular, reduces heavy metal or chemical-metered oxidant, prevents generation of chemical waste