Kit for clopidogrel personalized medicine related gene SNP detection, and detection method thereof

Kit for clopidogrel personalized medicine related gene SNP detection, and detection method thereof

The invention discloses a kit for clopidogrel personalized medicine related gene SNP detection and a detection method thereof. The kit comprises two forward primers and a reverse primer for detecting gene CYP2C19* 2 locus, and two forward primers and a reverse primer for detecting gene CYP2C19*3 loc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: TAO RAN, LI TONGEN, WANG BINGXIAO, WANG JINGJING, SUN YING, ZHU BING, WANG JIANGANG, LIU ZHIPEI
Format: Patent
Sprache:chi ; eng
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:The invention discloses a kit for clopidogrel personalized medicine related gene SNP detection and a detection method thereof. The kit comprises two forward primers and a reverse primer for detecting gene CYP2C19* 2 locus, and two forward primers and a reverse primer for detecting gene CYP2C19*3 locus. With the kit of the present invention, the two loci can be subjected to the high-throughput detection, and the genotyping result can be intuitively discerned through the software so as to quantitatively control the clopidogrel measurement and minimize the side effect. 本发明公开了种用于氯吡格雷个体化用药相关基因SNP检测的试剂盒及其检测方法，所述试剂盒包括检测基因CYP2C19*2位点的两条正向引物及条反向引物，和检测基因CYP2C19*3位点两条正向引物和条反向引物。本发明的试剂盒，可以对上述两个位点进行高通量检测，基因分型的结果可以通过软件直观的进行分辨，从而达到对氯吡格雷计量量化的控制，最大程度的降低副作用的目的。