Phosphorescent iridium complex probe having mitochondrial targeting function as well as preparation and application thereof

The invention relates to a phosphorescent iridium complex probe having a mitochondrial targeting function as well as a preparation method and an application thereof, in particular to a phosphorescent iridium complex probe containing a mitochondrial targeting group and a ClO recognition group as well...

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Bibliographische Detailangaben
Hauptverfasser: ZHAO QIANG, DI LONGKANG, LIU SHUJUAN, YANG JIGUANG, CHEN JIAN, XU WENJUAN, YANG JING, HUANG WEI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a phosphorescent iridium complex probe having a mitochondrial targeting function as well as a preparation method and an application thereof, in particular to a phosphorescent iridium complex probe containing a mitochondrial targeting group and a ClO recognition group as well as an application of the probe, and belongs to the technical field of organic photoelectric functional materials. The complex material comprises an oxime group-containing cyclometalated ligand, a metal center and an N^N ligand of the mitochondrial targeting group containing triphenylphosphine and has the general structural formula shown in the specification. Material synthesis steps are simple, material synthesis conditions are mild, and the probe has very good application prospect in ClO detection, mitochondrial targeting imaging and biological marking. 本发明涉及种具有线粒体靶向功能的磷光铱配合物探针及其制备方法和应用,具体涉及类既含有线粒体靶向基团又含有次氯酸根(ClO)识别基团的磷光铱配合物探针及其应用,属于有机光电功能材料技术领域。该类配合物材料由含肟基团的环金属配体、金属中心和含有三苯基膦的线粒体靶向基团的N^N配体组成,结构通式如下式所示。该材料合成