Medicine composition and preparation of gabexate mesylate and preparation method thereof

The invention relates to the field of medicine preparations and especially relates to a medicine composition and a preparation of gabexate mesylate and a preparation method thereof. In the invention, only are the gabexate mesylate, mannitol, acetic acid and water for injection are employed, wherein the usage amount of the mannitol is reduced, so that freeze-drying time is reduced and the cost is reduced. The preparation method has good stability and is suitable for industrial production. The product is less in side effects and has stable quality. 本发明涉及药物制剂领域，特别涉及甲磺酸加贝酯的药物组合物、制剂及其制备方法。本发明中用仅用到了甲磺酸加贝酯、甘露醇和醋酸及注射用水，甘露醇用量降低，冻干时间缩短。成本降低。本方法稳定性好，适合工业化生产，产品副作用少，质量稳定。