Preparation method of conductive hydrogel capable of controlling drug release
The invention discloses a preparation method of conductive hydrogel capable of controlling drug release and belongs to the technical field of biological materials. The preparation method comprises the steps that double-bonded biological macromolecules are subjected to photo-initiated double-bond pol...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses a preparation method of conductive hydrogel capable of controlling drug release and belongs to the technical field of biological materials. The preparation method comprises the steps that double-bonded biological macromolecules are subjected to photo-initiated double-bond polymerization to form a hydrogel base body, the hydrogel base body is put in a pre-prepared conductive macromolecule monomer solution containing a drug, the hydrogel base body is soaked in an oxidizing agent solution to oxidize conductive macromolecules in the hydrogel after swelling equilibrium is reached through hydrogel adsorption, meanwhile the drug is doped in the conductive macromolecules, and accordingly the conductive hydrogel capable of controlling the drug release is prepared. The prepared hydrogel can regulate drug release time and dosage through an electric field. Due to the fact that the hydrogel base body formed through polymerization of the grafted and modified biological macromolecules is adopted, the |
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